XXV CONGRESSO SIRC 2025
CON IL PATROCINIO DI
CON IL CONTRIBUTO NON CONDIZIONANTE DI
PREMI XXV CONGRESSO
STRUTTURA DEL CONGRESSO
Il Congresso si articola in 8 Macroaree di ricerca comprendenti specifici simposi:
- Macroarea#1 Percorsi traslazionali nella tossicità e nella protezione cardiovascolare.
Symposium#1 Translational pathways in cardiovascular toxicity and protection.
- Macroarea#2 Percorsi traslazionali nello scompenso cardiaco e nell’ipertensione polmonare.
Symposium#2 Translational pathways in heart failure and pulmonary hypertension.
- Macroarea #3 Percorsi traslazionali nei disordini elettrici e meccanici del cuore.
Symposium#3 Translational pathways in electrical and mechanical cardiac disorders.
- Macroarea #4 Percorsi traslazionali nell’invecchiamento cardiovascolare e nelle differenze di genere.
Symposium #4 Translational pathways in cardiovascular aging and gender differences.
- Macroarea #5 Percorsi traslazionali nello sviluppo e nell’implementazione metodologica.
Symposium #5 Translational pathways in methodological development and implementation.
- Macroarea #6 Percorsi traslazionali nella neurocardiologia.
Symposium #6 Translational pathways in neurocardiology.
- Macroarea #7 Percorsi traslazionali nella cardioimmunologia e nel metabolismo cardiaco.
Symposium #7 Translational pathways in cardioimmunology and cardiac metabolism.
- Symposium #8 Percorsi traslazionali nelle nuove strategie terapeutiche.
Symposium #8 Translational pathways in novel therapeutic strategies.
PROGRAMMA
DAY 1 – AFTERNOON (23 October 2025)
🔹13.30 Opening Ceremony & Welcome Messages
🔹14.00 SIRC OPENING LECTURE
Chair: Vincenzo Lionetti, SIRC President and Scuola Superiore Sant’Anna, Pisa, Italy
Elisabetta Cerbai, University of Florence, Florence, Italy
“Inflammatory drivers and arrhythmogenic mechanisms: new insights from cell and zebrafish models”
🔹14.40 Cardiovascular Toxicity and Protection
Chair: Pasquale Pagliaro, University of Turin, Turin, Elena Guzzolino, National Research Council of Italy, Florence, Italy
🔹14.40 Jan Kyselovic, Comenius University Bratislava, Bratislava, Slovakia
“Pleiotropic Antifibrotic Actions of Atorvastatin: GATA4/MEF2C Modulation and MicroRNA Regulation”
🔹15.05 Lisa Alibrandi, Scuola Superiore Sant’Anna, Pisa, Italy
“Mitochondria-Rich Endothelial Vesicles Safeguard Cardiomyocytes from Doxorubicin Injury In Vitro”
🔹15.20 Matteo Sorge, University of Turin, Turin
“A new perspective on lipid metabolism regulation to promote cardiac resilience to stress”
15.35 Coffee Break and Poster View
🔹17.05 Heart Failure and Pulmonary Hypertension
Chair: Tommaso Angelone, University of Calabria, Rende; Rosalinda Madonna, University of Pisa, Pisa, Italy
🔹17.05 Konstantinos Lefkimmiatis, University of Pavia, Pavia and Veneto Institute of Molecular Medicine, Padua, Italy
“Linking Necroptosis to Heart Failure: The Role of the Catecholamine/cAMP axis”
🔹17.30 Marco Guazzi, University of Milan, Milan, Italy
“Pulmonary hypertension and right ventricular remodeling in HFpEF adn HFrEF”
🔹17.55 Emilia Monti, University of Pisa, Pisa, Italy
“Endothelial nitric oxide synthase deficiency drives changes in Galectin-3-binding protein isoforms and inflammatory response in endothelial cells under metabolic stress”
🔹18.10 Maria Antonietta Riemma, University of Campania “Luigi Vanvitelli”, Naples, Italy
Additional therapeutic benefits of H2S-Donor combined with Dapagliflozin in a model of heart failure with preserved ejection fraction (HFpEF)
🔹18.25 SIRC-IACS JOINT LECTURE
Chair: Elena Osto, Medical University of Graz, Graz, Austria
Grant N. Pierce, President of the International Academy of Cardiovascular Sciences (IACS)
“Nuclear protein translocation as a mechanism for modifying cardiovascular cell growth in health and disease.”
DAY 2 – MORNING (24 October 2025)
🔹08.30 Electrical & Mechanical Cardiac Disorders
Chair: Francesco Moccia, University of Molise, Campobasso; Daniela Sorriento, University of Naples Federico II, Naples, Italy
🔹08.30 Alessio Alogna, Charité – Universitätsmedizin Berlin, Berlin, Germany
“Inhalation-based nanotherapies for targeted heart failure treatment”
🔹08.55 Antonio Zaza, University of Milano-Bicocca, Milano, Italy
“SERCA dysregulation: at the border between electrical and mechanical instability”
🔹09.20 Marica Dente, University of Florence, Florence, Italy
“Modulation of cardiac contractility through molecules acting on the sarcoplasmic reticulum and the sarcomeres”
🔹09.35 Carlotta Ronchi, IRCCS Humanitas Research Hospital, Milan, Italy
“Distinct LMNA mutation effects in iPSC-cardiomyocyte subtypes unveil LMNA”
🔹09.50 STATE OF THE ART LECTURE
Chair: Lucio Barile, Cardiocentro Ticino Institute, Bellinzona, Switzerland
Mauro Giacca, King’s College London, London, UK
“RNA therapies for the heart”
10.20 Coffee Break
🔹10.40 Cardiovascular Aging & Gender Differences
Chair: Elena Osto, Medical University of Graz, Graz, Austria; Stefano Tarantini, University of Oklahoma Health Sciences Center, Oklahoma, USA
🔹10.40 Federica Piani, University of Bologna, Bologna, Italy
“Sex and gender in hypertension”
🔹11.05 Giuseppe Faraco, Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, USA
“Linking Immunity, Vascular Health, and Cognitive Function: mechanisms and implications for aging”
🔹11.30 Pamela Waked, Medical University of Graz, Graz
“Testosterone as a protective hormone in Systemic Sclerosis–associated Pulmonary Hypertension”
🔹11.45 Rosario Ignazio Statello, University of Parma, Parma, Italy
“Sex-specific cardiac electrophysiological remodeling influences the susceptibility to arrhythmias in elderly rats”
🔹12.00 MEET THE EXPERT
Chair: Elisa Di Pasquale, IRCCS Humanitas Research Hospital, Milan, Italy
Sanjiv Dhingra, University of Manitoba, Canada
“Allogeneic stem cells and immunomodulatory nanomaterials for cardiac repair”
12.30 Lunch & Poster View
DAY 2 – AFTERNOON (24 October 2025)
🔹14.15 Methodological Development & Implementation
Chair: Francesco Lodola, University of Milano-Bicocca, Milano; Michele Miragoli, University of Parma, Italy
🔹14.15 Leonardo Sacconi, Institute of Clinical Physiology (IFC), National Research Council, Florence, Italy
“Unifying cardiac electrophysiology and structural remodeling at the organ level”
🔹14.40 Daniele Catalucci, Institute of Genetic and Biomedical Research (IRGB) – UOS Milan, Milan, Italy
“Integrating Targeting and Delivery Strategies in Cardiovascular Therapeutics”
🔹15.05 Silvia Becca, University of Turin, Turin, Italy
“The speed of developmental chromatin topology dynamics during cardiomyogenesis is controlled by a GATA4-CTCF rheostat”
🔹15.20 Chiara Florindi, University of Milan-Bicocca, Milan, Italy
“Control of cardiac bioelectricity via a membrane-targeted photoswitch”
🔹15.35 Neurocardiology
Chair: Claudia Penna, University of Turin, Turin; Michele Samaja, University of Milan, Milan, Italy
🔹15.35 Alberto Giannoni, Scuola Superiore Sant’Anna, Pisa, Italy
“Neurocardiology: From the Pathophysiology of the Brain-Heart Axis to Treatment Innovation in Heart Failure”
🔹16.00 Alessandra Martello, Scuola Superiore Sant’Anna, Pisa, Italy
“Selective Dopaminergic Lesion Drives Early Left Ventricular Dysfunction in Experimental Parkinson’s Disease”
🔹16.15 Francesca Callegari, Mario Negri Institute of Pharmacological Research IRCCS, Ilan, Italy
“Characterization of neurobehavioral function in a mouse model of heart failure induced by acute myocardial infarction”
16.30 Coffee Break
🔹16.50 SIRC TRASLATIONAL REASERCH LECTURE
Chair: Francesco Lodola
Balwant S. Tuana, University of Ottawa, Canada
“Tail anchored protein SLMAP for cardiac growth and function”
🔹17.20 VALSALVA PRIZE LECTURE
Introduced by Vincenzo Lionetti, SIRC President and Scuola Superiore Sant’Anna, Pisa, Italy
🔹17.30 Giampaolo Morciano, Università degli Studi di Bari Aldo Moro, Bari, Italy
“When mitochondria let the heart down: mechanisms and therapeutic targets”
🔹18.00 SIRC Assembly Meeting
Evening Social Dinner
DAY 3 (25 October 2025)
🔹08.30 Cardioimmunology & Cardiac Metabolism
Chair: Alessandra Ghigo, University of Turin, Turin; Carmine Rocca, University of Calabria, Rende, Italy
🔹08.30 Martina Semenzato, University of Padua and Veneto Institute of Molecular Medicine, Padua, Italy
“Mitochondrial dynamics, autophagy and heart failure: a deeper connection”
🔹08.55 Marinos Kallikourdis, IRCCS Humanitas Research Hospital and Humanitas University, Milan, Italy
“Immunomodulatory mechanisms in ageing”
🔹09.20 Anna De Bartolo, University of Calabria, Cosenza, Italy
“Empagliflozin enhances metabolic status and preserves myocardial and coronary function in diabetic and non-diabetic rats subjected to myocardial ischemia/reperfusion injury”
🔹09.35 Chiara Rubeo, University of Turin, Turin, Italy
“RSK Contributes to Systemic Inflammation and Cardiac Injury in Sepsis”
🔹09.50 GUIDO TARONE LECTURE
Chair: Carlo Gabriele Tocchetti, University of Naples Federico II, Naples, Italy
Jean-Luc Balligand, Catholic University of Louvain, Louvain, Belgium
“Can stress also protect your heart? Unveiled role for an adrenoreceptor”
10.20 Coffee Break
🔹10.40 SIRC-ARCA JOINT LECTURE
Chair: Michele Samaja, University of Milan, Milan, Italy
Gaetano Thiene, University of Padua, Italy
“Arrhythmogenic cardiomyopathy, a concealed, genetic morbid entity, killer of athletes”
🔹11.10 Novel Therapeutic Strategies
Chair: Laura Sartiani, University of Florence, Florence, Vincenzo Lionetti, Scuola Superiore Sant’Anna, Pisa, Italy
🔹11.10 Gabriele Matteo D’Uva, University of Bologna and IRCCS Azienda Ospedaliero-Universitaria, Bologna, Italy
“Novel strategies for cardiac regeneration: harnessing growth factors and glucocorticoid receptor modulation”
🔹11.35 Paola Luisa Cattaneo, University of Milan, Milan, Italy
“Discovering novel targets to promote cardiac regeneration and control cardiac fibrosis”
🔹12.00 Claudia Maniezzi, University of Milan-Bicocca, Milan, Italy
“Cellular Consequences of Non-Ablative Radiotherapy, A Novel Approach to Ventricular Tachycardias”
🔹12.15 Laura Guerricchio, University of Genova, Genova, Italy
“Cardioprotective Effects of Source-Defined Human Amniotic Fluid Extracellular Vesicles Against Premature Cardiac Senescence”
12.30 RESEARCHER AWARDS CEREMONY
13.30 Final Remarks & Take-Home Messages
ASTRACT SUBMISSION
Sarà possibile sottomettere i propri Abstract a partire da lunedì 28 aprile 2025 e fino a lunedì 8 settembre 2025.
REGISTRAZIONE AL CONGRESSO
The Registration to the Meeting is mandatory to be enabled to attend the Sessions and the Conference events (Welcome Party, Lunches, Coffee Breaks, and Social Events). Paid Registration is also mandatory to have
the accepted Abstract included in the published Conference Proceedings and eventually Vascular Pharmacology. To this end it is mandatory to complete the registration process by the deadline of October the 1st,
2021.
Please follow the instructions herein described:
The registration procedure is as follow:
you must proceed with the Payment by Bank Transfer (IBAN: IT79Z0306909606100000174834).
“For transfers from non-EU countries, the BIC/SWIFT code ‘BCITITMM’ must be added.”
Send your payment receipt As Soon As Possible, as it takes some time to process the payment, to segreteriasirc@sirc-cardio.it.
Your payment should be received, preferably, by us on or before October 1st, 2025.
Failure to pay the required amount on this date could result in the exclusion of the Abstract(s) from the Conference Proceedings. Nevertheless, payment can be completed even at the meeting avenue by cash.
Conference Fees
SIRC 2025 conference fees cover: attendance of Conference Delegates to the Sessions of the Meeting, Welcome Reception & Conference material, all Conference Lunches, all Coffee Breaks.
I costi sono da intendersi come segue:
Before/After October 1st
Regular member registration 180/250 euro
Regular non-member registration 300/350 euro
Junior Member PhD student 100/150 euro
Junior Non-member PhD student 180/250 euro
College student registration 40/50 euro
One day registration
Regular Member/Non-member 100/150 euro
Junior Member/ Non-member PhD student 80/100 euro
APERTURA finestra Submission sulle 8 macroaree:
1 Maggio 2025
SCADENZA Submission:
1 Settembre 2025
* A Certificate must be send together to the Bank transfer receipt at segreteriasirc@sirc-cardio.it.
INFORMAZIONI GENERALI
Sede
I lavori si terranno presso il Palazzo Sersanti, 1° piano (Piazza Giacomo Matteotti, 8 – Imola (BO)), sito a 800 mt (10 minuti a piedi) dalla Stazione Ferroviaria di Imola (Piazzale Anselmo Marabini).
Parcheggio
Piazza Giacomo Matteotti è inserita in un’area pedonale e a traffico limitato.
SEZIONE IN ALLESTIMENTO
