SIRC - Società Italiana di Ricerche Cardiovascolari


Post-doctoral position in Vascular Biology

A two-years postdoc position is available in the group of Prof. Alessandro Fantin (Department of Biosciences, University of Milan) to study novel mechanisms in Vascular Biology by exploiting microfluidic devices, in vivo models and single cell studies.

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Long and narrow road to win over myocardial ischemia-reperfusion injury

Michele Samaja – Pasquale Pagliaro

Myocardial infarct (MI) is the world leading cause of morbidity and mortality. The MI severity depends on the extent of the ischemia-reperfusion injury (IRI) that occurs when oxygenated blood returns to tissue after a period of ischemia. A story of success, failure, and hope, the first recognition of IRI as a clinical entity dates back to the 70s [1]. Great hope to treat IRI came in 1986 when ischemic preconditioning (IPC) was discovered [2]. Since then, nearly 35,000 PubMed manuscripts published in the last 10 years met the search for “ischemia reperfusion” (PubMed), 11,300 of which were specifically devoted to IRI in the myocardium.

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