SIRC - Società Italiana di Ricerche Cardiovascolari


Long and narrow road to win over myocardial ischemia-reperfusion injury

Michele Samaja – Pasquale Pagliaro

Myocardial infarct (MI) is the world leading cause of morbidity and mortality. The MI severity depends on the extent of the ischemia-reperfusion injury (IRI) that occurs when oxygenated blood returns to tissue after a period of ischemia. A story of success, failure, and hope, the first recognition of IRI as a clinical entity dates back to the 70s [1]. Great hope to treat IRI came in 1986 when ischemic preconditioning (IPC) was discovered [2]. Since then, nearly 35,000 PubMed manuscripts published in the last 10 years met the search for “ischemia reperfusion” (PubMed), 11,300 of which were specifically devoted to IRI in the myocardium.

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Simposio SIF-SIRC

Venerdì 26 Novembre 2021 ore 14:30

Il link dell’evento sarà presto disponibile

“Novel signalling pathways and strategies to modulate cardiac function”

Chair: Pasquale Pagliaro (University of Turin) e Teresa Pasqua (University «Magna Graecia» of Catanzaro)

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